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The Promises Treatment Centers, estimates that between five and ten percent of the patients at his hospitals are helped by naltrexone. Those more than likely to receive it are people with a history of early relapse—individuals who have been treated before and have not had the opportunity to maintain sobriety for much more than four weeks. Using two separate drugs to lose weight naturally can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you should err to the side of caution and allow the FDA do its job and demand some research be done so that the public recognizes the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on their own medications. Researchers discovered that participants using this drug for the year, lost excess weight within four weeks and have kept the weight off during the entire 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, that might make them more effective and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular could be the fact that at the time of right now there aren't long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure level and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. 
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